PAMP-12 (Human)

M.W. 1618.9

C₇₇H₁₁₉N₂₅O₁₄

Phe – Arg – Lys – Lys – Trp – Asn – Lys – Trp – Ala – Leu – Ser – Arg – NH2

Hypotensive Peptide / Major endogenous form of PAMP PAMP-12 [PAMP (9-20)] is described as an endogenous and very potent dodeca peptide. It is identified as the C-terminus of Proadrenomedullin N-terminal 20 peptide or its gene related peptide Adrenomedullin . These peptides play an important role in hypertension diseases, often in combination with a normal renal function. It was reported that in cases of organ damage, accompanied by hypertension, the plasma concentration of PAMP-12 was significantly higher than in cases without organ damage. Captopril shows no effect on the levels of Adrenomedullin or PAMP-12 in plasma.

Synthetic Product

The purity is guaranteed to be higher than 99% by HPLC