Adrenomedullin (Rat)

Adrenomedullin (Rat)

0.1 mg
€205,00

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Adrenomedullin (Rat)

Adrenomedullin (Rat)

Product ID: 4281

Tyr – Arg – Gln – Ser – Met – Asn – Gln – Gly – Ser – Arg – Ser – Thr – Gly – Cys – Arg – Phe – Gly – Thr – Cys – Thr – Met – Gln – Lys – Leu – Ala – His – Gln – Ile – Tyr – Gln – Phe – Thr – Asp – Lys – Asp – Lys – Asp – Gly- Met – Ala – Pro – Arg – Asn – Lys – Ile – Ser – Pro – Gln – Gly – Tyr – NH2

€205,00
excl. 19% VAT
Quantity
Description

M.W. 5729.4

C242H381N77O75S5

Tyr – Arg – Gln – Ser – Met – Asn – Gln – Gly – Ser – Arg – Ser – Thr – Gly – Cys – Arg – Phe – Gly – Thr – Cys – Thr – Met – Gln – Lys – Leu – Ala – His – Gln – Ile – Tyr – Gln – Phe – Thr – Asp – Lys – Asp – Lys – Asp – Gly- Met – Ala – Pro – Arg – Asn – Lys – Ile – Ser – Pro – Gln – Gly – Tyr – NH2

The biological activity of this peptide is examinded by the Division of Pharmacology, Peptide Institute, Inc.Adrenomedullin (Rat) is a polypeptide amide of 50 amino acids instead of 52 amino acids for the corresponding human Adrenomedullin. It shows not only diuretic, natriuretic and vasodilatory activities, Adrenomedullin (Rat) has also some pro-apoptotic and anti-proliferative effects in mesangial cells. Dose-dependent antimicrobial activity against E. coli has been reported recently.

Synthetic Product (Disulfide bond between Cys14-Cys19)

The purity is guaranteed to be higher than 99% by HPLC

References:

1. J. Sakata, T. Shimokubo, K. Kitamura, S. Nakamura, K. Kangawa, H. Matsuo and T. Eto, Biochem. Biophys. Res. Commun. , 195, 921 (1993). (Original; cDNA & Biological Activity)

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