Alpha-Defensin-6 (Human)

Alpha-Defensin-6 (Human)

0.1 mg
€235,00

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Alpha-Defensin-6 (Human)
  • Alpha-Defensin-6 (Human)
  • Alpha-Defensin-6 (Human)

Alpha-Defensin-6 (Human)

Product ID: 4458

Ala – Phe – Thr – Cys – His – Cys – Arg – Arg – Ser – Cys – Tyr – Ser – Thr – Glu – Tyr – Ser – Tyr – Gly – Thr – Cys – Thr – Val – Met – Gly – Ile – Asn – His – Arg – Phe – Cys – Cys – Leu

€235,00
excl. 19% VAT
Description

α-Defensin-6 | HD-6 (Human Defensin-6)

M.W. 3708.2

C156H228N46O46S7

Ala – Phe – Thr – Cys – His – Cys – Arg – Arg – Ser – Cys – Tyr – Ser – Thr – Glu – Tyr – Ser – Tyr – Gly – Thr – Cys – Thr – Val – Met – Gly – Ile – Asn – His – Arg – Phe – Cys – Cys – Leu

HD-6 (Human) | Alpha-Defensin-6 (Human) was originally isolated from neobladder urine as a 32-residue peptide. Heliobacter pylori infection increases HD-6 expression. Peptide inhibits herpes simplex virus infection and has influenza A virus neutralizing ability. In Crohn´s disease patients show reduced alpha-Defensin-6 level.

Synthetic Product (disulfide bonds between Cys4-Cys31, Cys6-Cys20 and Cys10-Cys30)

The purity of alpha-Defensin-6 is guaranteed to be higher than 99% by HPLC

References:

1. D.E. Jones and C.L. Bevins, FEBS Lett., 315, 187 (1993) 2. E.M. Porter, M.A. Poles, J.S. Lee, J. Naitoh, C.L. Bevins and T. Ganz, FEBS Lett. 434, 272 (1998) (Endogenous Form) 3. E. Hazrati, B. Galen, W. Lu, W. Wang, Y. Ouyang, M.J. Keller, R.I. Lehrer and B.C. Herold, J. Immunol., 177, 8658 (2006) (Pharmacol. inhibition herpes simplex virus infection)

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