Elafin (Human)

M.W. 5999.1

C₂₅₄H₄₁₆N₇₂O₇₅S₁₀

Ala – Gln – Glu – Pro – Val – Lys – Gly – Pro – Val – Ser – Thr – Lys – Pro – Gly – Ser – Cys – Pro – Ile – Ile – Leu – Ile – Arg – Cys – Ala – Met – Leu – Asn – Pro – Pro – Asn – Arg – Cys – Leu – Lys – Asp – Thr – Asp – Cys – Pro – Gly – Ile – Lys – Lys – Cys – Cys – Glu – Gly – Ser – Cys – Gly – Met – Ala – Cys – Phe – Val – Pro – Gln

Elafin | Elastase-Specific Inhibitor from Human Skin The human derived polypeptide Elafin is expressed in human skin, lungs, and mammary glands. It was first isolated from human epithelia. Elafin is a reversible, strong binding inhibitor of human leukocyte proteinase and elastase. Elafin represents a new type of elastase inhibitor with anti-microbial activity against Gram- positive and Gram-negative bacteria. Often used synonyms for Elafin: ESI (Elastase-specific Inhibitor), SKALP ( Skin-derived Antileukoproteinase ) and Protease Inhibitor WAP3. Elafin offered from PeptaNova is a chemically manufactured peptide and not recombinat from yeast or bacterial cell culture, therefore cross contamination must not be feared. Elafin specific Antiserum is available from PeptaNova as well

Synthetic Product (disulfide bonds between Cys16-Cys45, Cys23-Cys49, Cys32-Cys44and Cys38-Cys53)

The purity is guaranteed to be higher than 99% by HPLC

Shipping | Storage | Stability Elafin will be shipped at room temperature and long term storage at -20°C is recommended. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing by preparing aliquots.