PAMP-12 (Human)

PAMP-12 (Human)

0.5 mg
€78,00

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PAMP-12 (Human)
  • PAMP-12 (Human)
  • PAMP-12 (Human)

PAMP-12 (Human)

Product ID: 4339

Phe – Arg – Lys – Lys – Trp – Asn – Lys – Trp – Ala – Leu – Ser – Arg – NH2

€78,00
excl. 19% VAT
Description

Proadrenomedullin N-terminal 20 Peptide (Human, 9 – 20)

M.W. 1618.9

C77H119N25O14

Phe – Arg – Lys – Lys – Trp – Asn – Lys – Trp – Ala – Leu – Ser – Arg – NH2

Hypotensive Peptide / Major endogenous form of PAMP PAMP-12 [PAMP (9-20)] is described as an endogenous and very potent dodeca peptide. It is identified as the C-terminus of Proadrenomedullin N-terminal 20 peptide or its gene related peptide Adrenomedullin . These peptides play an important role in hypertension diseases, often in combination with a normal renal function. It was reported that in cases of organ damage, accompanied by hypertension, the plasma concentration of PAMP-12 was significantly higher than in cases without organ damage. Captopril shows no effect on the levels of Adrenomedullin or PAMP-12 in plasma.

Synthetic Product

The purity is guaranteed to be higher than 99% by HPLC

References:

1. K. Kuwasato, K. Kitamura, Y. Ishiyama, H. Washimine, J. Kato, K. Kangawa and T. Eto, FEBS Lett., 414, 105 (1997) (Original)

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