Pleiotrophin (Human)

Pleiotrophin (Human)

50 μg
€260,00

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Pleiotrophin (Human)

Pleiotrophin (Human)

Product ID: 4335

Gly – Lys – Lys – Glu – Lys – Pro – Glu – Lys – Lys – Val – Lys – Lys – Ser – Asp – Cys – Gly – Glu – Trp – Gln – Trp – Ser – Val – Cys – Val – Pro – Thr – Ser – Gly – Asp – Cys – Gly – Leu – Gly – Thr – Arg – Glu – Gly – Thr – Arg – Thr – Gly – Ala – Glu – Cys – Lys – Gln – Thr – Met – Lys – Thr – Gln – Arg – Cys – Lys – Ile – Pro – Cys – Asn – Trp – Lys – Lys – Gln – Phe – Gly – Ala – Glu – Cys – Lys – Tyr – Gln – Phe – Gln – Ala – Trp – Gly – Glu – Cys – Asp – Leu – Asn – Thr – Ala – Leu – Lys – Thr – Arg – Thr – Gly – Ser – Leu – Lys – Arg – Ala – Leu – His – Asn – Ala – Glu – Cys – Gln – Lys – Thr – Val – Thr – Ile – Ser – Lys – Pro – Cys – Gly – Lys – Leu – Thr – Lys – Pro – Lys – Pro – Gln – Ala – Glu – Ser – Lys – Lys – Lys – Lys – Lys – Glu – Gly – Lys – Lys – Gln – Glu – Lys – Met – Leu – Asp

€260,00
excl. 19% VAT
Quantity
Description

PTN (human)

M.W. 15302.6

C658H1079N197O198S12

Gly – Lys – Lys – Glu – Lys – Pro – Glu – Lys – Lys – Val – Lys – Lys – Ser – Asp – Cys – Gly – Glu – Trp – Gln – Trp – Ser – Val – Cys – Val – Pro – Thr – Ser – Gly – Asp – Cys – Gly – Leu – Gly – Thr – Arg – Glu – Gly – Thr – Arg – Thr – Gly – Ala – Glu – Cys – Lys – Gln – Thr – Met – Lys – Thr – Gln – Arg – Cys – Lys – Ile – Pro – Cys – Asn – Trp – Lys – Lys – Gln – Phe – Gly – Ala – Glu – Cys – Lys – Tyr – Gln – Phe – Gln – Ala – Trp – Gly – Glu – Cys – Asp – Leu – Asn – Thr – Ala – Leu – Lys – Thr – Arg – Thr – Gly – Ser – Leu – Lys – Arg – Ala – Leu – His – Asn – Ala – Glu – Cys – Gln – Lys – Thr – Val – Thr – Ile – Ser – Lys – Pro – Cys – Gly – Lys – Leu – Thr – Lys – Pro – Lys – Pro – Gln – Ala – Glu – Ser – Lys – Lys – Lys – Lys – Lys – Glu – Gly – Lys – Lys – Gln – Glu – Lys – Met – Leu – Asp

Pleiotrophin (Human) – PTN | Heparin-Binding Growth Factor (Neurite Outgrowth-Promoting Factor) Pleiotrophin (PTN) belongs together with Midkine to the Heparin-Binding Growth Factor (Neurite Outgrowth-Promoting Factor) family. PTN is expressed in the central and peripheral nervous system during embryonic and postnatal development. Additionally, Pleiotrophin plays an important role in tumor angionesis and is involved as growth and angiogenetic factor in onset, invasion, and metastatic process of many tumors. Pleiotrophin, manufactured at Peptide Institute Inc. is a synthetic peptide of high purity and not made by recombinant technichs.

Synthetic Product (Disulfide bonds between Cys15– Cys44, Cys23– Cys53, Cys30– Cys57, Cys67– Cys99, and Cys77– Cys109)

The purity is guaranteed to be higher than 99% by HPLC

Shipping | Storage | Stability Our product Pleiotrophin will be shipped at room temperature. Information about product specific storage conditions will be found on the vial. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing by preparing aliquots.

References:

1. TY.-S. Li, P.G. Milner, A.K. Chauhan, M.A. Watson, R.M. Hoffman, C.M. Kodner, J. Milbrandt and T.F. Deuel, Science, 250, 1690 (1990) (Pleiotrophin Primary Structure) 2. P.G. Milner, D. Shah, R. Veile, H. Donis-Keller and B.V. Kumar, Biochemistry, 31, 12023 (1992) (Nucleotide Seq.; Human) 3. F. Czubayko, A.M. Schulte, G.J. Berchem and A. Wellstein, Proc. Natl. Acad. Sci. USA, 93, 14753 (1996) (Pharmacol.) 4. T. Inui, M. Nakao, H. Nishio, Y. Nishiuchi, S. Kojima, T. Muramatsu, T. Kimura and S. Sakakibara, J. Peptide Res., 55, 384 (2000) (Chem. Synth. and S-S Bond of Pleiotrophin)

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