Z-Leu-Arg-AMC

Z-Leu-Arg-AMC

5 mg
€95,00

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Z-Leu-Arg-AMC

Z-Leu-Arg-AMC

Product ID: 3210

Benzyloxycarbonyl- L-leucyl- L-arginine 4-methylcoumaryl-7-amide

€95,00
excl. 19% VAT
Quantity
Description

Z-LR-AMC | Z-Leu-Arg-MCA

M.W. 578,66

C30H38N6O6

Benzyloxycarbonyl- L-leucyl- L-arginine 4-methylcoumaryl-7-amide

Substrate for Cathepsin K / S / V The Benzyloxycarbonyl-protected Dipeptide Z-Leu-Arg-AMC was carfully manufactured at Peptide Institute and is a widly used fluorogenic substrate for Cathepsine K, S and V. (Z-Leu-Arg-MCA is used in Japan as synonym for Z-Leu-Arg-AMC)

Synthetic Product (Hydrochloride Form)

A trace of impurity might be detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 2 %.

References:

1. D. Brömme, K. Okamoto, B.B. Wang and S. Biroc, J. Biol. Chem., 271, 2126 (1996) 2. D. Brömme, Z. Li, M. Barnes and E. Mehler, Biochemistry, 38, 2377 (1999)

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