Amylin (Human)

Amylin (Human)

0.5 mg
€295,00

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Amylin (Human)

Amylin (Human)

Product ID: 4219

Lys – Cys – Asn – Thr – Ala – Thr – Cys – Ala – Thr – Gln – Arg – Leu – Ala – Asn – Phe – Leu – Val – His – Ser – Ser – Asn – Asn – Phe – Gly – Ala – Ile – Leu – Ser – Ser – Thr – Asn – Val – Gly – Ser – Asn – Thr – Tyr – NH2

€295,00
excl. 19% VAT
Quantity
Description

IAPP (Islet Amyloid Polypeptide) | DAP (Diabetes-Associated Peptide)

M.W. 3903.3

C165H261N51O55S2

122384-88-7

Lys – Cys – Asn – Thr – Ala – Thr – Cys – Ala – Thr – Gln – Arg – Leu – Ala – Asn – Phe – Leu – Val – His – Ser – Ser – Asn – Asn – Phe – Gly – Ala – Ile – Leu – Ser – Ser – Thr – Asn – Val – Gly – Ser – Asn – Thr – Tyr – NH2

Amylin (Human) is a 37 mer polypeptide with two disulfid bridges, which shows suplementary activities to insulin. This peptide hormone called Islet amyloid polypeptide (IAPP) or alternatively Amylin was secreted by pancreatic β-cells like insulin or glucagon depending to food intake.

Synthetic Product (Disulfide bonds between Cys2-Cys7)

The purity of Amylin (Human) is guaranteed to be higher than 97% by HPLC

References:

1. P. Westermark, C. Wernstedt, E. Wilander, D.W. Hayden, T.D. O´Brian and K.H. Johnson, Proc. Natl. Acad. Sci. USA, 84, 3881 (1987) (Original) 2. G.J.S. Cooper, A.C. Willis, A. Clark, R.C. Turner, R.B. Sim and K.B.M. Reid, Proc. Natl. Acad. Sci. USA, 84, 8628 (1987) (Original; Complete Sequence of Amylin) 3. A. Clark, G.J.S. Cooper, C.E. Lewis, F.J. Morris, A.C. Willis, K.B.M. Reid and R.C. Turner, Lancet, 2, 231 (1987) (Pathologics)

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