Iberiotoxin

Iberiotoxin

0.1 mg
€175,00

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Iberiotoxin
  • Iberiotoxin
  • Iberiotoxin

Iberiotoxin

Product ID: 4235

Pyr – Phe – Thr – Asp – Val – Asp – Cys – Ser – Val – Ser – Lys – Glu – Cys – Trp – Ser – Val – Cys – Lys – Asp – Leu – Phe – Gly – Val – Asp – Arg – Gly – Lys – Cys – Met – Gly – Lys – Lys – Cys – Arg – Cys – Tyr – Gln

€175,00
excl. 19% VAT
Description

(Scorpion, Buthus tamulus)

M.W. 4230.8

C179H274N50O55S7

129203-60-7

Pyr – Phe – Thr – Asp – Val – Asp – Cys – Ser – Val – Ser – Lys – Glu – Cys – Trp – Ser – Val – Cys – Lys – Asp – Leu – Phe – Gly – Val – Asp – Arg – Gly – Lys – Cys – Met – Gly – Lys – Lys – Cys – Arg – Cys – Tyr – Gln

Iberiotoxin (IbTX), originally isolated from the venom of the scorpion buthus tamulus, is a potent Ca2+-activated K+ Channel Blocker (Maxi-K+ Channel Blocker). IbTX offered from PeptaNova is a chemically manufactured peptide and not isolated from animal origin or from recombinant sources.The biological activity of Iberiotoxin (IbTX) is examined by the Division of Pharmacology, Peptide Institute, Inc.

Synthetic Product (disulfide bonds between Cys7-Cys28, Cys13-Cys33 and Cys17-Cys35)

The purity of IbTX is guaranteed to be higher than 99% by HPLC

Shipping | Storage | Stability Iberiotoxin (IbTX) will be shipped at room temperature. Information about product specific storage conditions will be found on the vial. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing.

References:

1. A. Galvez, G. Gimenez-Gallego, J.P. Reuben, L. Roy-Contancin, P. Feigenbaum, G.J. Kaczorowski and M.L. Garcia, J. Biol. Chem., 265, 11083 (1990) (Original) 2. M.L. Garcia, A. Galvez, M. Garcia-Calvo, V.F. King, J. Vazquez and G. J. Kaczorowski, J. Bioenerg. Biomembr., 23, 615 (1991) (Review) 3. K.M. Giangiacomo, M.L. Garcia and O.B. McManus, Biochemistry., 31, 6719 (1992) (Pharmacol.) 4. K.G. J. Kaczorowski, H.-G. Kaus, R.J. Leonard, O.B. McManus and M.L. Garcia, J. Bioenerg. Biomembr., 28, 255 (1996) (Review, Iberiotoxin)

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