ω-Agatoxin TK

ω-Agatoxin TK

0.1 mg
€295,00

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ω-Agatoxin TK
  • ω-Agatoxin TK
  • ω-Agatoxin TK

ω-Agatoxin TK

Product ID: 4294

Glu – Asp – Asn – Cys – Ile – Ala – Glu – Asp – Tyr – Gly – Lys – Cys – Thr – Trp – Gly – Gly – Thr – Lys – Cys – Cys – Arg – Gly – Arg – Pro – Cys – Arg – Cys – Ser – Met – Ile – Gly – Thr – Asn – Cys – Glu – Cys – Thr – Pro – Arg – Leu – Ile – Met – Glu – Gly – Leu – D-Ser – Phe – Ala

€295,00
excl. 19% VAT
Description

omega-Agatoxin-TK | ω-Aga-TK (Funnel Web Spider, Agelenopsis aperta)

M.W. 5273.0

C215H337N65O70S10

145017-83-0

Glu – Asp – Asn – Cys – Ile – Ala – Glu – Asp – Tyr – Gly – Lys – Cys – Thr – Trp – Gly – Gly – Thr – Lys – Cys – Cys – Arg – Gly – Arg – Pro – Cys – Arg – Cys – Ser – Met – Ile – Gly – Thr – Asn – Cys – Glu – Cys – Thr – Pro – Arg – Leu – Ile – Met – Glu – Gly – Leu – D-Ser – Phe – Ala

omega-Agatoxin TK is a selective channel blocker for the P-type Ca2+ ChannelThe neuropeptide toxin omega-Agatoxin TK was originally isolated in the venom of the funnel web spider Agelenopsis aperta. Omega-Aga-TK from Peptide Institute is a syntheic peptide, manufactured by chemical peptide synthesis and is not isolated from animal sources.Omega-Agatoxin IVB is often used as synonym for Omega-Agatoxin TK.

Synthetic Product (Disulfide bonds between Cys4-Cys20, Cys12-Cys25, Cys19-Cys36 and Cys27-Cys34)

The purity is guaranteed to be higher than 99% by HPLC

References:

1. M. Kuweda, T. Teramoto, K.J. Kumagaye, K. Nakajima, T. Watanabe, T. Kawai, Y. Kawakami, T. Niidome, K. Sawada, Y. Nishizawa and K. Katayama, Mol. Pharmacol, 46, 587 (1994) (Original) 2. Y. Shikata, T. Watanabe, T. Teramoto, A. Inoue, Y. Kawakami, Y. Nishizawa, K. Katayama and M. Kuweda, J. Biol. Chem., 270, 16719 (1995) (L-Ser to D-Ser Isomerase) 3. T. Kozaki, M. Kuweda, M. Narukawa, Y. Nagai and N. Asakawa, Peptide Chemistry 1995, 245 (1996) (Pharmacol.) 4. T. Teramoto, T. Nidome, M. Kimura, M. Ohgoh, Y. Nishizawa, K. Katayama, T. Mayumi and K. Saweda, Brain. Res., 7456, 225 (1997) (Pharmacology of omega-Agatoxin TK.)

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