Uroguanylin (Human)

Uroguanylin (Human)

0.1MG
€101,00

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Uroguanylin (Human)
  • Uroguanylin (Human)
  • Uroguanylin (Human)

Uroguanylin (Human)

Product ID: 4295

Asn – Asp – Asp – Cys – Glu – Leu – Cys – Val – Asn – Val – Ala – Cys – Thr – Gly – Cys – Leu

€101,00
excl. 19% VAT
Description

M.W. 1667.9

C64H102N18O26S4

154525-25-4

Asn – Asp – Asp – Cys – Glu – Leu – Cys – Val – Asn – Val – Ala – Cys – Thr – Gly – Cys – Leu

Intestinal peptide hormone | Regulator for electrolyte/fluid transport in the gastrointestinal epitheliumHuman uroguanylin is a 16 mer intestinal peptide with 2 disulfide bonds and acts as a potent guanylate Cylase C agonist. Uroguanylin shows a very high structural similarity to the heat resistant E.Coli Enterotoxin (STa).

Synthetic Product (disulfide bonds between Cys4-Cys12 and Cys7-Cys15)

The purity is guaranteed to be higher than 99% by HPLC

References:

1. T. Kita, C.E. Smith, K.F. Fok, K.L. Duffin, W.M. Moore, P.J. Karabatsos, J.F. Kachur, F.K. Hamra, N.V. Pidhorodeckyj, L.R. Forte and M.G. Currie, Am. J. Physiol., 266, F342 (1994) (Original) 2. M. Nakazato, H. Yamaguchi, H. Kinoshita, K. Kangawa, H. Matsuo, N. Chino and S. Matsukura, Biochem. Biophys. Res. Commun., 220, 586 (1996) (Biologically Active / Inactive isomer) 3. H. Kinoshita, S. Fujimoto, M. Nakazato, N. Yokota, Y. Date, H. Yamaguchi, S. Hisanaga and T. Eto, Kidney Int., 52, 1028 (1997) (Urine and Plasma Level of Uroguanylin; Renal Disease) 4. N. Chino, S. Kubo, T. Kitani, T. Yoshida, R. Tanabe, Y. Kobayashi, M. Nakazato, K. Kangawa and T. Kimura, FEBS Lett., 421, 27 (1998) (Biochemistry of Uroguanylin; Topological Isomers)

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