{"title":"Antimicrobial Peptides","description":"\u003cp\u003e\u003cstrong\u003eDefensin\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003epeptides are essential members of host-defense\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eantimicrobial peptides\u003c\/strong\u003e. These cationic peptides are originally produced by vertebrates, insects and higher plants. Host defense peptides are involved in the protection against different kind of pathogens like bacteria, fungi and several viruses and play an important role in inflammation and wound repair. Antitumor activity of dedicated antimicrobial peptides is described in combination with non-immunogenic tumor antigens.\u003cbr\u003eThe human defensin group is composed of two subclasses: Peptanova offers six different\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003ealpha-Defensin\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003epeptides (HNP; HD) and four\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003ebeta-Defensin\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003epeptides (hBD), which are characterized by their distinct arrangement of three disulfide bonds.\u003c\/p\u003e\n\u003cp\u003eThe antimicrobial peptide\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eLL-37\u003c\/strong\u003e, which is derived from the C-terminus of the human cathelicidin and\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eDermcidin-1L human (DCD-1L)\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eare available as new members of this group of antimicrobial active peptides (\u003cspan\u003e \u003c\/span\u003eLEAP- Hepcidin\u003cspan\u003e \u003c\/span\u003e).\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/en\/products\/elafin-human\" title=\"Elafin (Human)\"\u003eElafin (Human)\u003cspan\u003e \u003c\/span\u003e\u003c\/a\u003e, cysteine rich peptide composed of 57 amino acid residues. Elastase specific inhibitor with potent antimicrobial and antiproteolytic activities.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNew, available since February 2013:\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003eCatestatin (Human) | Chromogranin A (Human, 352-372)\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003eAntimicrobial Peptide \/ Regulator of Blood Pressure \/ Cardiac Function\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNew, available since March 2012:\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003eAMP-IBP5 (Human)\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e| Insulin-Like Growth Factor-Binding Protein 5 (Human, 193-214 Amide)\u003c\/p\u003e\n\u003cp\u003eAll offered antimicrobial peptides are of synthetic origin and not isolated from bioplogical sources or made by biotechnical procedures. Defensin peptides and Cathelicidin Antimicrobial Peptide LL-37 are usually available from our stock in Germany within short time.\u003c\/p\u003e\n\u003cp\u003eIn addition to this group of host defense peptides, PeptaNova offers the two Liver Expressed Antimicrobial Peptides (LEAP-1 and LEAP-1), which will be found in a separate chapter.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAntimicrobial peptides\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003emanufactured by Peptide Institute Inc, Osaka Japan will be shipped at room temperature to our customers in Europe. These conditions are tested for years and will not have any negative influence on the quality of the peptides.\u003c\/p\u003e","products":[{"product_id":"beta-defensin-1-human","title":"Beta-Defensin-1 (Human)","description":"\u003cp\u003ehBD-1 | Human β-Defensin-1\u003c\/p\u003e","brand":"peptanova","offers":[{"title":"0.1 mg","offer_id":52785937613142,"sku":"4337-S","price":266.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/7940\/1302\/files\/4337-s.jpg?v=1777022262"},{"product_id":"alpha-defensin-1-human","title":"Alpha-Defensin-1 (Human)","description":"\u003cp\u003eα-Defensin-1 | HNP-1 (Human Neutrophil Peptide-1)\u003c\/p\u003e","brand":"peptanova","offers":[{"title":"0.1 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