Ac-DEVD-CHO

Ac-DEVD-CHO

5 mg
€148,00

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Ac-DEVD-CHO
  • Ac-DEVD-CHO
  • Ac-DEVD-CHO

Ac-DEVD-CHO

Product ID: 3172

Acetyl- L-aspartyl- L-glutaminyl- L-threonyl- L-aspart-1-al

€148,00
excl. 19% VAT
Description

M.W. 502.48

C20H30N4O11

184179-08-6

Acetyl- L-aspartyl- L-glutaminyl- L-threonyl- L-aspart-1-al

Reversible inhibitor for Caspase-3/7/8 The frequently used Caspase 3/7 inhibitors from type DEVD are similar to a short partial sequence of the DNA repair enzyme Poly (ADP- ribose) polymerase. The reversible inhibitor Ac-DEVD-CHO is corresponding to the related and often used AMC substrate Ac-DEVD-AMC code: 3171-v. Both peptides the inhibitor and the substrate are available for prompt delivery ex stock Sandhausen.

Synthetic Product

References:

1. D.W. Nicholson, A. Ali, N.A. Thornberry, J.P. Vaillancourt, C.K. Ding, M. Gallant, Y. Gareau, P.R. Griffin, M. Labelle, Y.A. Lazebnik, N.A. Munday, S.M. Raju, M.E. Smulson, T.-T. Yamin, V.L. Yu and D.K. Miller, Nature, 376, 37 (1995) 2. M. Enari, R.V. Talanian, W.W. Wong and S. Nagata, Nature, 380, 723 (1996) 3. N.A. Thornberry, T.A. Rano, E.P. Peterson, D.M. Rasper, T. Timkey, M. Garcia-Calvo, V.M. Houtzager, P.A. Nordstrom, S. Roy, J.P. Vaillancourt, K.T. Chapman and D.W. Nicholson, J. Biol. Chem., 272, 17907 (1997)

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