Beta-Defensin-2 (Human)

M.W. 4328.2

C₁₈₈H₃₀₅N₅₅O₅₀S₆

Gly – Ile – Gly – Asp – Pro – Val – Thr – Cys – Leu – Lys – Ser – Gly – Ala – Ile – Cys – His – Pro – Val – Phe – Cys – Pro – Arg – Arg – Tyr – Lys – Gln – Ile – Gly – Thr – Cys – Gly – Leu – Pro – Gly – Thr – Lys – Cys – Cys – Lys – Lys – Pro

This antimicrobial peptide Human Beta-Defensin-2 specific for Gram-Negative Bacteria and effective for Candida albicans was originally isolated from skin cells from Psoriasis-patients. The expression of hBD-2 by skin cells is a direct response to a local infection by Pseudomonas aeruginosa or other bacteria. Peptide LL-37 and hBD-2 might be able to protect the skin of patients with psoriasis and both peptides may be involved in the pathogenesis of psoriasis. Additionally beta-Defensin-2 is suspected to play a distinct role in Crohn’s disease. Beta-Defensin-2 (human) offered from PeptaNova is a chemical synthesized peptide of highest purity for medical and biological research. 4338-s (0.1 mg) Beta-Defensin-2 manufactured by Peptide Institute, Inc. is available for prompt delivery ex stock Germany.

Synthetic Product (disulfide bonds between Cys8-Cys37, Cys15-Cys30 and Cys20-Cys38)

The purity of Human Beta-Defensin-2 is guaranteed to be higher than 99% by HPLC