Guanylin (Rat, Mouse)

Product ID: 4275

Pro – Asn – Thr – Cys – Glu – Ile – Cys – Ala – Tyr – Ala – Ala – Cys – Thr – Gly – Cys

€85,00

excl. 19% VAT

Description

M.W. 1515.7

C₆₀H₉₀N₁₆O₂₂S₄

Pro – Asn – Thr – Cys – Glu – Ile – Cys – Ala – Tyr – Ala – Ala – Cys – Thr – Gly – Cys

Guanylin (Rat, Mouse) is a 15 mer endogenous intestinal Peptide. It is a potent Cyclase C Activator and plays a role in the electrolyte secretion and regulation of water.

Synthetic Product (disulfide bonds between Cys4-Cys12 and Cys7-Cys15)

The purity is guaranteed to be higher than 99% by HPLC

References:

1. M.G. Currie, K.F. Fok, J. Kato, R.J. Moore, F.K. Hamra, K.L. Duffin, and C.E. Smith, Proc. Natl. Acad. Sci. USA., 89, 947 (1992) (Original; Guanylin Rat) 2. R.C. Wiegand, J. Kato and M.G. Currie, Biochem. Biophys. Res. Commun., 185, 812 (1992) (Original; Rat cDNA) 3. S. Schults, T.D. Chrisman and D.L. Garbers, . Biol. Chem., 267, 16019 (1992) (Tissue Distribution) 4. F.J. de Sauvage, S. Keshav, W.-J. Kuang, N. Gillett, W. Henzel and D.V. Goeddel, Proc. Natl. Acad. Sci. USA., 89, 9089 (1992) (Original; Guanylin Mouse cDNA)

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