Pentosidine

Pentosidine

1 mg
€139,00

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Pentosidine
  • Pentosidine
  • Pentosidine

Pentosidine

Product ID: 3242

(S)-2-Amino-6-(2-(((S)-4-amino-4-carboxybutyl)amino)-4H-imidazo[4,5-b]pyridin-4-yl)hexanoic acid (Trifluoroacetate Form)

€139,00
excl. 19% VAT
Description

M.W. 378.43

C17H26N6O4

124505-87-9

(S)-2-Amino-6-(2-(((S)-4-amino-4-carboxybutyl)amino)-4H-imidazo[4,5-b]pyridin-4-yl)hexanoic acid (Trifluoroacetate Form)

Advanced Glycation End Product (AGE) / Biomarker for Glycation-Oxidative Stress e.g. in Diabetes

Synthetic Product

A trace of impurity might be detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 2 %.

References:

1. D.R. Sell and V.M. Monnier, J. Bio. Chem., 264, 21597 (1989) Original 2. T. Miyata, Y. Ueda, K. Horie, M. Nangaku, S. Tanaka, C.Y. Strihou, and K. Kurokawa, Kitney Int., 53, 416 (1998) (Pharmacol.) 3. D. Slowik-Żylka, K. Safranow, V. Dziedziejko, H. Bukowska, K. Ciechanowski, and D. Chlubek, J. Biochem. Biophys. Methods, 61, 313 (2004) (Specific determination of Pentosidine in plasma) 4. M. Saito and K. Marumo, Osteoporos. Int., 21, 195 (2010) (clinical review) 5. R. Furuya, H. Kumagai, T. Miyata, H. Fukasawa, S. Isobe, N. Kinoshita, and A. Hishida, Clin. Exp. Nephrol., 16, 421 (2012) (clinical; correlation to Cardiovascular risk) 6. M. Yamamoto and T. Sugimoto, Curr. Osteoporos. Rep., 14, 320 (2016) (Review)

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