Sarafotoxin B

Sarafotoxin B

0.1 mg
€120,00

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Sarafotoxin B
  • Sarafotoxin B
  • Sarafotoxin B

Sarafotoxin B

Product ID: 4206

Cys – Ser – Cys – Lys – Asp – Met – Thr – Asp – Lys – Glu – Cys – Leu – Tyr – Phe – Cys – His – Gln – Asp – Val – Ile – Trp

€120,00
excl. 19% VAT
Description

Sarafotoxin S6b | SRTX-B
(Snake, Atractaspis engaddensis)

M.W. 2563.9

C110H159N27O34S5

120972-53-4

Cys – Ser – Cys – Lys – Asp – Met – Thr – Asp – Lys – Glu – Cys – Leu – Tyr – Phe – Cys – His – Gln – Asp – Val – Ile – Trp

Endothelin Related Peptide | The synthetic peptide Sarafotoxin B (S6b, SRTX-B) manufactured by Peptide Institute Inc. was initially isolated from Snake, Atractaspis engaddensis and shows a very close structural and functional relationship to Endothelin-2 , which can be ordered as well from PeptaNova. The vasoconstictive effects induced by Sarafotoxin S6b seems to be weaker and not as long lasting.The biological activity of Sarafotoxin S6b is examined by the Division of Pharmacology, Peptide Institute, Inc.

Synthetic Product Trifluoracetate Form (disulfide bonds between Cys1– Cys15 and Cys3– Cys11)

The purity is guaranteed to be higher than 99% by HPLC

References:

1. PC. Takasaki, N. Tamiya, A. Bdolah, Z. Wollberg and E. Kochva, Toxicon., 26, 543 (1988) (Original; Chem. Structure of Sarafotoxin B) 2. JY. Kloog, I. Ambar, M. Sokolovsky, E. Kochva, Z. Wollberg and A. Bdolah, Science, 242, 268 (1988) (Original; Biochem.) 3. K. Nakajima, S. Kumagaye, H. Nishio, H. Kuroda, T.X. Watanabe, Y. Kobayashi, H. Tamaoki, T. Kimura and S. Sakakibara, J. Cardiovasc. Pharmacol., 13, S8 (1989) (Chem. Synthesis & Biological Activity of Sarafotoxin) 4. T.X. Watanabe, Y. Itahara, K. Nakajima, S. Kumagaye, T. Kimura, and S. Sakakibara, J. Cardiovasc. Pharmacol., 17 (Suppl.7), S5 (1991) (Pharmacology of Sarafotoxin)

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