Stichodactyla Toxin

Stichodactyla Toxin

0.1 mg
€145,00

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Stichodactyla Toxin

Stichodactyla Toxin

Product ID: 4287

Arg – Ser – Cys – Ile – Asp – Thr – Ile – Pro – Lys – Ser – Arg – Cys – Thr – Ala – Phe – Gln – Cys – Lys – His – Ser – Met – Lys – Tyr – Arg – Leu – Ser – Phe – Cys – Arg – Lys – Thr – Cys – Gly – Thr – Cys

€145,00
excl. 19% VAT
Quantity
Description

ShK (Sea Anemone, Stichodactyla helianthus)

M.W. 4054.8

C169H274N54O78S7

Arg – Ser – Cys – Ile – Asp – Thr – Ile – Pro – Lys – Ser – Arg – Cys – Thr – Ala – Phe – Gln – Cys – Lys – His – Ser – Met – Lys – Tyr – Arg – Leu – Ser – Phe – Cys – Arg – Lys – Thr – Cys – Gly – Thr – Cys

Voltage-Dependent K+ Channel (A Channel) BlockerStichodactyla Toxin (ShK) is a 35-residue polypeptide originally isolated from the sea anemone Stichodactyla helianthus venom. It is a selective ion channel blocker for different types of voltage-gated potassium channels. Stichodactyla Toxin (ShK) manufactured at Peptide Institute Inc. is from chemical origin and not made by recombinant methods, therefore crosscontamination with E. Coli protein residues must not to be apprehanded.

Synthetic Product (disulfide bonds between Cys3– Cys35, Cys12– Cys28 and Cys17– Cys32 )

The purity is guaranteed to be higher than 99% by HPLC

Shipping | Storage | Stability Our product Stichodactyla Toxin will be shipped at room temperature. Information about product specific storage conditions will be found on the vial. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing by preparing aliquots.

References:

1. E. Karlsson, A.L. Harvey, A. Aneiros and O. Castaneda, Toxicon, 31, 504 (1993) (Original) 2. J. Pohl, F. Hubalek, M.E. Byrnes, K.R. Nielsen, A. Woods and M.W. Pennington, Lett. Pept. Sci., 1, 291 (1994) (S-S Bond) 3. Castañeda, V.Sotolongo, A.M. Amor, R. Stöcklin, A.J. Anderson, A.L. Harvey, Å. Engström, C. Wernstedt and E. Karlsson, Toxicon, 33, 603 (1995) (Pharmacon.)

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