Stresscopin (Human)

M.W. 4367.1

C₁₉₅H₃₂₆N₅₆O₅₃S₂

Thr – Lys – Phe – Thr – Leu – Ser – Leu – Asp – Val – Pro – Thr – Asn – Ile – Met – Asn – Leu – Leu – Phe – Asn – Ile – Ala – Lys – Ala – Lys – Asn – Leu – Arg – Ala – Gln – Ala – Ala – Ala – Asn – Ala – His – Leu – Met – Ala – Gln – Ile – NH2

Selective Ligand for Type 2 CRF Receptors Stresscopin, is described as a specific ligand for the corticotropin-releasing hormone receptor type 2 and is a homologous peptide of Stresscopin-Related Peptide (or Urocortin II code 4383-s). It was thus postulated to be a 40 amino acid residue peptide, which follows the amide-donating Gly residue and then the Arg-Lys-Lys processing signal in the gene sequence. An amino terminal truncated peptide (des-Thr-Lys), or urocortin III [Proc. Natl. Acad. Sci. USA, 98, 7570 (2001)], was proposed soon after the publication of stresscopin. All five of these peptides, have just been proposed from the gene sequence; therefore, the exact processing sites of these peptides should be determined by isolating the corresponding endogenous peptides.

Synthetic Product

The purity of our product Stresscopin, code 4387-s is guaranteed to be higher than 99% by HPLC