AAF-CMK

AAF-CMK

5 mg
€85,00

Vous pouvez créer un devis après avoir ajouté le produit au panier.

Passer aux informations sur le produit
AAF-CMK
  • AAF-CMK
  • AAF-CMK

AAF-CMK

ID du produit: 3202

L-Alanyl- L-alanyl- L-phenylalanyl- chloromethane (Trifluoroacetate Form)

€85,00
excl. 19% TVA
Description

Ala-Ala-Phe-CH2Cl | Ala-Ala-Phe-chloromethylketone

M.W. 339.82

C16H22N3O3Cl

102129-66-8

L-Alanyl- L-alanyl- L-phenylalanyl- chloromethane (Trifluoroacetate Form)

Irreversible Inhibitor for Tripeptidyl Peptidase II (Component of Giant Protease with Some Proteasome Function), Chymotrypsin and Chymase The synthetic serine protease inhibitor AAF-CMK, code 3202-v inhibits tripeptidyl peptidase II (TPP II) irreversibly and inhibits TPP I reversibly. Interference of this Tripeptidyl peptidase II (TPPII) with the chymotrypsin-like activity of the proteasome seems to be negligible. Inhibition of bleomycin hydrolase by inhibitor AAF-CMK is reported.

Synthetic Product

Références:

1. R. Glas, M. Bogyo, J.S. McMaster, M. Gaczynska and H.L. Ploegh, Nature, 392, 618 (1998) 2. E. Geier, G. Pfeifer, M. Wilm, M. Lucchiari-Hartz, W. Baumeister, K. Eichmann and G. Niedermann, Science, 283, 978 (1999) 3. D. Leung, G. Abbenante and D.P. Fairlie, J. Med. Chem. 43, 305 (2000) 4. C. Rose et al, Neuropeptides 28, 157 (1995)

Téléchargements

Vous pourriez aussi aimer