KYT-1

KYT-1

1 mg
€315,00

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KYT-1
  • KYT-1
  • KYT-1

KYT-1

Produkt-ID: 4395

(3S)- N- [(1S)- 5- Amino- 1- (N,N- dimethylcarbamoyl)pentyl]- 3- [(2S)- 6- amino- 2- (benzyloxycarbonyl) aminohexanoylamino]- 6- guanidino- 2- oxohexanamide

€315,00
exkl. 19% MwSt.
Beschreibung

Carbobenzoxy-Lys-Arg-CO-Lys-N-(CH3)2

M.W. 619.76

C29H49N9O6

(3S)- N- [(1S)- 5- Amino- 1- (N,N- dimethylcarbamoyl)pentyl]- 3- [(2S)- 6- amino- 2- (benzyloxycarbonyl) aminohexanoylamino]- 6- guanidino- 2- oxohexanamide

Inhibitor for Arg-GingipainThe cysteine protinases Arg-gingipain and Lys-gingipain where produced from bacterium Porphyromonas gingivalis. Carbobenzoxy-Lys-Arg-CO-Lys-N-(CH3)2 (KYT-1) can be used as potent and selective inhibitor against Arg-gingipain, whereas Lys-gingipain is blocked selectively by the small peptide Carbobenzoxy-Glu(NHN(CH3)Ph)-Lys-CO-NHCH2Ph (KYT-36).

Synthetic Product (Hydrochloride Form)

Referenzen:

1. T. Kadowaki, A. Baba, N. Abe, R. Takii, M. Hashimoto, T. Tsukuba, S. Okazaki, Y. Suda, T. Asao and K.Yamamoto, Mol. Pharmacol, 66, 1599 (2004) (Original)

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